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Which of the following provides the body with its first line of defense against infection?

  1. Keratinocytes

  2. Tendons

  3. Immune cells

  4. Stratum granulosum

The correct answer is: Immune cells

The initial line of defense against infection is provided by immune cells. While keratinocytes do play a role in protecting the body from external threats, such as UV radiation and dehydration, they are not the first line of defense against infection. Tendons, which connect muscles to bones, and the stratum granulosum, which is a layer of skin, do not contribute to the body's defense system. It is important to note that other structures and processes such as mucus, saliva, and tears also provide initial defense mechanisms, but immune cells are primarily responsible for recognizing and destroying harmful pathogens.